Acute Coronary Syndrome

AEGIS II

"Study to Investigate CSL112 in Subjects with Acute Coronary Syndrome (AEGIS II)"

Investigator: Earl Hope, MD

The purpose of this study is to evaluate the efficacy of CSL112 on reducing the risk of MACE (CV death, MI, or stroke) from the time of randomization through 90 days in subjects with ACS (diagnosed with STEMI or NSTEMI).

Learn more about the AEGIS II trial.

View on ClinicalTrials.gov or call the Clinical Trials Office at 484-628-8585 for more information.


Heart Failure

GUIDE-HF

"Hemodynamic-GUIDEd Management of Heart Failure"

Investigator: Jared Green, DO

The purpose of this study is to demonstrate the effectiveness of the CardioMEMS™ Heart Failure System in an expanded patient population, including patients with New York Heart Association (NYHA) Class II, III, or IV heart failure with or without a prior hospitalization.

Learn more about the GUIDE-HF trial.

View on ClinicalTrials.gov or call the Clinical Trials Office at 484-628-8585 for more information.


OPTIMIZER Smart

"OPTIMIZER Smart Post-Approval Study"

Investigator: Jared Green, DO

The purpose of this post approval study (PAS) is to evaluate the safety of the long-term use of the OPTIMIZER Smart device and Cardiac Contractility Modulation therapy on the quality of life and heart failure symptoms for patients who remain symptomatic despite optimized guideline directed heart failure medications.

Learn more about the OPTIMIZER Smart study.

View on ClinicalTrials.gov, Impulse-Dynamics, and FDA.gov or call the Clinical Trials Office at 484-628-8585 for more information.


REHAB-HF

"A Trial of Rehabilitation Therapy in Older Acute Heart Failure Patients"

Investigator: Jared Green, DO

The purpose of this study is to measure the effect of an exercising training program has on physical function, hospital readmission rates and medical costs for people admitted to the hospital with a diagnosis of heart failure. This study is closed to enrollment.

Learn more about the REHAB-HF trial .

View on ClinicalTrials.gov or call the Clinical Trials Office at 484-628-8585 for more information.